SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

Bedell Frazier Investment Counselling, LLC's Holding History (CIK: 0001388142)

Note: Option positions (PUT/CALL) are excluded.

Q4 2017
Shares 18,992 Value ($000) $2,946 Avg Close — Range —
Q3 2017
Shares 27,995 Value ($000) $4,287 Avg Close — Range —
Q2 2017
Shares 26,388 Value ($000) $4,361 Avg Close — Range —
Q1 2017
Shares 26,068 Value ($000) $4,542 Avg Close — Range —
Q4 2016
Shares 22,638 Value ($000) $3,857 Avg Close — Range —
Q3 2016
Shares 21,733 Value ($000) $4,213 Avg Close — Range —
Q3 2014
Shares 1,631 Value ($000) $423 Avg Close — Range —
Q2 2014
Shares 39,055 Value ($000) $9,197 Avg Close — Range —
Q1 2014
Shares 39,570 Value ($000) $5,877 Avg Close — Range —
Q4 2013
Shares 39,710 Value ($000) $5,611 Avg Close — Range —
Q3 2013
Shares 39,810 Value ($000) $4,773 Avg Close — Range —