SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

EVENTIDE ASSET MANAGEMENT, LLC's Holding History (CIK: 0001442891)

Note: Option positions (PUT/CALL) are excluded.

Q1 2014
Shares 9,800 Value ($000) $1,456 Avg Close — Range —
Q4 2013
Shares 6,400 Value ($000) $904 Avg Close — Range —