SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

Twin Tree Management, LP's Holding History (CIK: 0001535588)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018
Shares 8,545 Value ($000) $1,277 Avg Close — Range —
Q2 2017
Shares 2,623 Value ($000) $434 Avg Close — Range —
Q1 2017
Shares 3,548 Value ($000) $618 Avg Close — Range —
Q4 2016
Shares 21,572 Value ($000) $3,675 Avg Close — Range —
Q3 2016
Shares 19,247 Value ($000) $3,731 Avg Close — Range —
Q1 2016
Shares 8,843 Value ($000) $1,520 Avg Close — Range —
Q3 2015
Shares 18,276 Value ($000) $3,751 Avg Close — Range —
Q2 2015
Shares 2,552 Value ($000) $616 Avg Close — Range —
Q3 2014
Shares 18,185 Value ($000) $4,711 Avg Close — Range —
Q2 2014
Shares 43,742 Value ($000) $10,301 Avg Close — Range —
Q1 2014
Shares 11,228 Value ($000) $1,668 Avg Close — Range —
Q4 2013
Shares 26,154 Value ($000) $3,695 Avg Close — Range —
Q3 2013
Shares 36,268 Value ($000) $4,348 Avg Close — Range —
Q2 2013
Shares 2,259 Value ($000) $215 Avg Close — Range —
Q1 2013
Shares 3,132 Value ($000) $286 Avg Close — Range —
Q4 2012
Shares 12,788 Value ($000) $1,179 Avg Close — Range —