SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

Point72 Asset Management, L.P.'s Holding History (CIK: 0001603466)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018
Shares 84,000 Value ($000) $12,549 Avg Close — Range —
Q4 2017
Shares 556,880 Value ($000) $86,383 Avg Close — Range —
Q3 2017
Shares 209,300 Value ($000) $32,052 Avg Close — Range —
Q2 2017
Shares 267,300 Value ($000) $44,177 Avg Close — Range —
Q1 2017
Shares 144,750 Value ($000) $25,220 Avg Close — Range —
Q4 2016
Shares 410,700 Value ($000) $69,975 Avg Close — Range —
Q3 2016
Shares 224,900 Value ($000) $43,599 Avg Close — Range —
Q2 2016
Shares 130,100 Value ($000) $23,949 Avg Close — Range —
Q1 2016
Shares 197,200 Value ($000) $33,899 Avg Close — Range —
Q4 2015
Shares 115,800 Value ($000) $23,739 Avg Close — Range —
Q3 2015
Shares 100 Value ($000) $21 Avg Close — Range —
Q1 2015
Shares 4,600 Value ($000) $1,101 Avg Close — Range —