SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC's Holding History (CIK: 0001644956)

Note: Option positions (PUT/CALL) are excluded.

Q3 2017
Shares 92,554 Value ($000) $14,174 Avg Close — Range —
Q2 2017
Shares 93,811 Value ($000) $15,504 Avg Close — Range —
Q1 2017
Shares 95,862 Value ($000) $16,702 Avg Close — Range —
Q4 2016
Shares 125,531 Value ($000) $21,388 Avg Close — Range —
Q3 2016
Shares 144,468 Value ($000) $28,007 Avg Close — Range —
Q2 2016
Shares 183,614 Value ($000) $33,800 Avg Close — Range —
Q1 2016
Shares 197,277 Value ($000) $33,912 Avg Close — Range —
Q4 2015
Shares 196,182 Value ($000) $40,217 Avg Close — Range —
Q3 2015
Shares 166,321 Value ($000) $34,134 Avg Close — Range —