SHUTTLE PHARMACTCLS HLDGS IN

CUSIP: 825693203 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2022
Shares 11,772 Value ($000) $23 Avg Close — Range —
Q3 2022
Shares 32,808 Value ($000) $151 Avg Close — Range —