SIENNA BIOPHARMACEUTICALS IN

Ticker: SNNAQ CUSIP: 82622H108 Class: COM

STATE STREET CORP's Holding History (CIK: 0000093751)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019

Shares 235,967 Value ($000) $547 Avg Close $2.71 Range $2.05 - $3.80

Q4 2018

Shares 227,818 Value ($000) $529 Avg Close $8.82 Range $2.23 - $15.18

Q3 2018

Shares 232,226 Value ($000) $3,441 Avg Close $15.89 Range $12.77 - $18.05

Q2 2018

Shares 218,598 Value ($000) $3,322 Avg Close $16.98 Range $14.33 - $21.53

Q1 2018

Shares 207,026 Value ($000) $3,888 Avg Close $17.48 Range $13.37 - $20.99

Q4 2017

Shares 46,259 Value ($000) $840 Avg Close $21.15 Range $15.22 - $26.00

Q3 2017

Shares 26,307 Value ($000) $586 Avg Close $21.95 Range $18.50 - $29.25

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2019	235,967	$547	$2.71	$2.05 - $3.80
Q4 2018	227,818	$529	$8.82	$2.23 - $15.18
Q3 2018	232,226	$3,441	$15.89	$12.77 - $18.05
Q2 2018	218,598	$3,322	$16.98	$14.33 - $21.53
Q1 2018	207,026	$3,888	$17.48	$13.37 - $20.99
Q4 2017	46,259	$840	$21.15	$15.22 - $26.00
Q3 2017	26,307	$586	$21.95	$18.50 - $29.25