SIENNA BIOPHARMACEUTICALS IN

Ticker: SNNAQ CUSIP: 82622H108 Class: COM

STATE OF WISCONSIN INVESTMENT BOARD's Holding History (CIK: 0000854157)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019

Shares 20,900 Value ($000) $48 Avg Close $2.71 Range $2.05 - $3.80

Q4 2018

Shares 16,100 Value ($000) $37 Avg Close $8.82 Range $2.23 - $15.18

Q3 2018

Shares 16,100 Value ($000) $239 Avg Close $15.89 Range $12.77 - $18.05

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2019	20,900	$48	$2.71	$2.05 - $3.80
Q4 2018	16,100	$37	$8.82	$2.23 - $15.18
Q3 2018	16,100	$239	$15.89	$12.77 - $18.05