SIERRA ONCOLOGY INC

CUSIP: 82640U107 Class: COMMON

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2019
Shares 147,700 Value ($000) $51 Avg Close — Range —
Q3 2019
Shares 158,800 Value ($000) $62 Avg Close — Range —
Q2 2019
Shares 71,500 Value ($000) $40 Avg Close — Range —
Q1 2019
Shares 35,900 Value ($000) $61 Avg Close — Range —
Q4 2018
Shares 23,500 Value ($000) $31 Avg Close — Range —
Q3 2018
Shares 41,400 Value ($000) $70 Avg Close — Range —
Q2 2018
Shares 40,600 Value ($000) $120 Avg Close — Range —
Q4 2017
Shares 11,600 Value ($000) $43 Avg Close — Range —