SINGULAR GENOMICS SYSTEMS IN

CUSIP: 82933R100 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q1 2023
Shares 23,100 Value ($000) $28 Avg Close — Range —
Q4 2022
Shares 34,300 Value ($000) $69 Avg Close — Range —
Q3 2022
Shares 45,000 Value ($000) $113 Avg Close — Range —
Q2 2022
Shares 77,300 Value ($000) $295 Avg Close — Range —