SIO GENE THERAPIES INC

CUSIP: 829399104 Class: COMMON

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2022
Shares 70,925 Value ($000) $31 Avg Close — Range —
Q3 2022
Shares 70,925 Value ($000) $20 Avg Close — Range —
Q2 2022
Shares 71,025 Value ($000) $26 Avg Close — Range —
Q1 2022
Shares 95,446 Value ($000) $64 Avg Close — Range —
Q4 2021
Shares 30,607 Value ($000) $39 Avg Close — Range —
Q3 2021
Shares 173,137 Value ($000) $376 Avg Close — Range —
Q2 2021
Shares 365,392 Value ($000) $998 Avg Close — Range —
Q1 2021
Shares 548,153 Value ($000) $1,431 Avg Close — Range —