SIO GENE THERAPIES INC

CUSIP: 829399104 Class: COMMON

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022
Shares 55,838 Value ($000) $37 Avg Close — Range —
Q4 2021
Shares 71,238 Value ($000) $92 Avg Close — Range —
Q3 2021
Shares 88,801 Value ($000) $193 Avg Close — Range —
Q2 2021
Shares 302,101 Value ($000) $825 Avg Close — Range —
Q1 2021
Shares 323,401 Value ($000) $844 Avg Close — Range —