SOLENO THERAPEUTICS INC

CUSIP: 834203200 Class: COMM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q2 2022
Shares 149,546 Value ($000) $28 Avg Close — Range —
Q1 2022
Shares 208,546 Value ($000) $47 Avg Close — Range —
Q4 2021
Shares 309,546 Value ($000) $127 Avg Close — Range —
Q3 2021
Shares 365,846 Value ($000) $338 Avg Close — Range —
Q2 2021
Shares 218,252 Value ($000) $249 Avg Close — Range —
Q1 2021
Shares 361,530 Value ($000) $456 Avg Close — Range —
Q4 2020
Shares 507,618 Value ($000) $980 Avg Close — Range —
Q3 2020
Shares 592,606 Value ($000) $1,487 Avg Close — Range —
Q2 2020
Shares 48,380 Value ($000) $107 Avg Close — Range —