SOPHIRIS BIO INC

CUSIP: 83578Q209 Class: FOREIGN CANADIAN

FIRST MANHATTAN CO. LLC.'s Holding History (CIK: 0000728083)

Note: Option positions (PUT/CALL) are excluded.

Q3 2014
Shares 353,686 Value ($000) $1,036 Avg Close — Range —
Q2 2014
Shares 605,142 Value ($000) $1,355 Avg Close — Range —
Q1 2014
Shares 751,842 Value ($000) $2,503 Avg Close — Range —
Q4 2013
Shares 1,000,500 Value ($000) $3,701 Avg Close — Range —
Q3 2013
Shares 1,000,500 Value ($000) $4,682 Avg Close — Range —