SOPHIRIS BIO INC

CUSIP: 83578Q209 Class: FOREIGN CANADIAN

Artal Group S.A.'s Holding History (CIK: 0001053906)

Note: Option positions (PUT/CALL) are excluded.

Q3 2014
Shares 1,000,000 Value ($000) $2,930 Avg Close — Range —
Q2 2014
Shares 1,000,000 Value ($000) $2,240 Avg Close — Range —
Q1 2014
Shares 1,000,000 Value ($000) $3,330 Avg Close — Range —
Q4 2013
Shares 1,000,000 Value ($000) $3,700 Avg Close — Range —
Q3 2013
Shares 1,000,000 Value ($000) $4,680 Avg Close — Range —