SOPHIRIS BIO INC

CUSIP: 83578Q209 Class: FOREIGN CANADIAN

BVF INC/IL's Holding History (CIK: 0001056807)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 1,060,283 Value ($000) $614 Avg Close — Range —
Q4 2014
Shares 1,060,283 Value ($000) $573 Avg Close — Range —
Q3 2014
Shares 600,000 Value ($000) $1,758 Avg Close — Range —
Q2 2014
Shares 600,000 Value ($000) $1,344 Avg Close — Range —
Q1 2014
Shares 600,000 Value ($000) $1,998 Avg Close — Range —
Q4 2013
Shares 600,000 Value ($000) $2,220 Avg Close — Range —
Q3 2013
Shares 600,000 Value ($000) $2,808 Avg Close — Range —