SOPHIRIS BIO INC

CUSIP: 83578Q209 Class: FOREIGN CANADIAN

MILLENNIUM MANAGEMENT LLC's Holding History (CIK: 0001273087)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018
Shares 104,627 Value ($000) $210 Avg Close — Range —
Q4 2017
Shares 199,705 Value ($000) $453 Avg Close — Range —
Q1 2017
Shares 37,100 Value ($000) $105 Avg Close — Range —
Q4 2016
Shares 23,200 Value ($000) $65 Avg Close — Range —
Q3 2016
Shares 34,680 Value ($000) $108 Avg Close — Range —