SPARK THERAPEUTICS INC

CUSIP: 84652J103 Class: COM

Itau Unibanco Holding S.A.'s Holding History (CIK: 0001132597)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 396 Value ($000) $15 Avg Close — Range —
Q4 2018
Shares 396 Value ($000) $15 Avg Close — Range —
Q3 2018
Shares 460 Value ($000) $25 Avg Close — Range —