SPARK THERAPEUTICS INC

CUSIP: 84652J103 Class: COM

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q3 2019
Shares 751,927 Value ($000) $72,922 Avg Close — Range —
Q2 2019
Shares 751,927 Value ($000) $76,982 Avg Close — Range —
Q1 2019
Shares 751,927 Value ($000) $85,629 Avg Close — Range —
Q4 2018
Shares 1,384,130 Value ($000) $54,175 Avg Close — Range —
Q3 2018
Shares 1,384,130 Value ($000) $75,504 Avg Close — Range —
Q2 2018
Shares 1,384,130 Value ($000) $114,551 Avg Close — Range —
Q1 2018
Shares 1,384,130 Value ($000) $92,169 Avg Close — Range —
Q4 2017
Shares 1,384,130 Value ($000) $71,172 Avg Close — Range —
Q3 2017
Shares 1,384,130 Value ($000) $123,409 Avg Close — Range —
Q2 2017
Shares 1,318,341 Value ($000) $78,758 Avg Close — Range —
Q1 2017
Shares 1,318,341 Value ($000) $70,320 Avg Close — Range —
Q4 2016
Shares 1,318,341 Value ($000) $65,785 Avg Close — Range —
Q3 2016
Shares 1,318,341 Value ($000) $79,180 Avg Close — Range —
Q2 2016
Shares 1,318,341 Value ($000) $67,407 Avg Close — Range —
Q1 2016
Shares 1,262,382 Value ($000) $37,253 Avg Close — Range —
Q4 2015
Shares 1,262,382 Value ($000) $57,199 Avg Close — Range —
Q3 2015
Shares 1,262,382 Value ($000) $52,679 Avg Close — Range —
Q2 2015
Shares 1,262,382 Value ($000) $76,084 Avg Close — Range —
Q1 2015
Shares 1,327,451 Value ($000) $102,878 Avg Close — Range —