SYNAGEVA BIOPHARMA CORP

CUSIP: 87159A103 Class: COM

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 15,501 Value ($000) $1,512 Avg Close — Range —
Q4 2014
Shares 13,905 Value ($000) $1,290 Avg Close — Range —
Q3 2014
Shares 14,280 Value ($000) $982 Avg Close — Range —
Q2 2014
Shares 13,858 Value ($000) $1,452 Avg Close — Range —
Q1 2014
Shares 14,860 Value ($000) $1,232 Avg Close — Range —
Q4 2013
Shares 14,716 Value ($000) $953 Avg Close — Range —
Q3 2013
Shares 13,624 Value ($000) $862 Avg Close — Range —
Q2 2013
Shares 13,902 Value ($000) $584 Avg Close — Range —