SYNERGY PHARMACEUTICALS DEL

CUSIP: 871639308 Class: COM

US BANCORP \DE\'s Holding History (CIK: 0000036104)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 180 Value ($000) $0 Avg Close — Range —
Q3 2018
Shares 180 Value ($000) $0 Avg Close — Range —
Q2 2018
Shares 180 Value ($000) $0 Avg Close — Range —
Q1 2018
Shares 180 Value ($000) $0 Avg Close — Range —
Q4 2017
Shares 180 Value ($000) $0 Avg Close — Range —
Q3 2017
Shares 1,480 Value ($000) $4 Avg Close — Range —
Q2 2017
Shares 1,480 Value ($000) $7 Avg Close — Range —
Q1 2017
Shares 1,480 Value ($000) $7 Avg Close — Range —
Q4 2016
Shares 180 Value ($000) $1 Avg Close — Range —
Q3 2016
Shares 6,655 Value ($000) $37 Avg Close — Range —
Q2 2016
Shares 6,655 Value ($000) $26 Avg Close — Range —
Q1 2016
Shares 6,655 Value ($000) $18 Avg Close — Range —
Q4 2015
Shares 6,655 Value ($000) $38 Avg Close — Range —
Q3 2015
Shares 6,655 Value ($000) $35 Avg Close — Range —
Q2 2015
Shares 8,055 Value ($000) $66 Avg Close — Range —
Q1 2015
Shares 180 Value ($000) $1 Avg Close — Range —
Q4 2014
Shares 180 Value ($000) $1 Avg Close — Range —
Q3 2014
Shares 180 Value ($000) $1 Avg Close — Range —
Q2 2014
Shares 180 Value ($000) $1 Avg Close — Range —
Q1 2014
Shares 1,180 Value ($000) $6 Avg Close — Range —
Q4 2013
Shares 180 Value ($000) $1 Avg Close — Range —
Q3 2013
Shares 180 Value ($000) $1 Avg Close — Range —
Q2 2013
Shares 180 Value ($000) $1 Avg Close — Range —