SYNERGY PHARMACEUTICALS DEL

CUSIP: 871639308 Class: COM

STATE STREET CORP's Holding History (CIK: 0000093751)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 4,341,539 Value ($000) $495 Avg Close — Range —
Q3 2018
Shares 11,450,205 Value ($000) $19,468 Avg Close — Range —
Q2 2018
Shares 12,698,842 Value ($000) $22,098 Avg Close — Range —
Q1 2018
Shares 19,895,860 Value ($000) $36,408 Avg Close — Range —
Q4 2017
Shares 20,454,646 Value ($000) $45,613 Avg Close — Range —
Q3 2017
Shares 13,178,208 Value ($000) $38,218 Avg Close — Range —
Q2 2017
Shares 12,933,104 Value ($000) $57,552 Avg Close — Range —
Q1 2017
Shares 12,626,115 Value ($000) $58,841 Avg Close — Range —
Q4 2016
Shares 6,283,669 Value ($000) $38,270 Avg Close — Range —
Q3 2016
Shares 5,630,316 Value ($000) $31,026 Avg Close — Range —
Q2 2016
Shares 5,182,008 Value ($000) $19,689 Avg Close — Range —
Q1 2016
Shares 3,666,776 Value ($000) $10,119 Avg Close — Range —
Q4 2015
Shares 3,815,852 Value ($000) $21,634 Avg Close — Range —
Q3 2015
Shares 5,105,071 Value ($000) $27,056 Avg Close — Range —
Q2 2015
Shares 1,767,664 Value ($000) $14,670 Avg Close — Range —
Q1 2015
Shares 1,735,502 Value ($000) $8,018 Avg Close — Range —
Q4 2014
Shares 1,718,686 Value ($000) $5,241 Avg Close — Range —
Q3 2014
Shares 3,955,968 Value ($000) $11,017 Avg Close — Range —
Q2 2014
Shares 4,963,086 Value ($000) $20,197 Avg Close — Range —
Q1 2014
Shares 3,387,686 Value ($000) $17,991 Avg Close — Range —
Q4 2013
Shares 1,332,346 Value ($000) $7,501 Avg Close — Range —
Q3 2013
Shares 1,236,933 Value ($000) $5,654 Avg Close — Range —
Q2 2013
Shares 947,596 Value ($000) $4,095 Avg Close — Range —