SYNERGY PHARMACEUTICALS DEL

CUSIP: 871639308 Class: COM

STATE OF WISCONSIN INVESTMENT BOARD's Holding History (CIK: 0000854157)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 256,600 Value ($000) $29 Avg Close — Range —
Q3 2018
Shares 164,000 Value ($000) $279 Avg Close — Range —
Q2 2018
Shares 164,000 Value ($000) $285 Avg Close — Range —
Q1 2018
Shares 164,000 Value ($000) $300 Avg Close — Range —
Q4 2017
Shares 164,000 Value ($000) $366 Avg Close — Range —
Q3 2017
Shares 164,000 Value ($000) $476 Avg Close — Range —
Q2 2017
Shares 164,000 Value ($000) $730 Avg Close — Range —