SYNERGY PHARMACEUTICALS DEL

CUSIP: 871639308 Class: COM

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 13,359 Value ($000) $2 Avg Close — Range —
Q3 2018
Shares 168,864 Value ($000) $287 Avg Close — Range —
Q4 2017
Shares 28,964 Value ($000) $65 Avg Close — Range —
Q3 2017
Shares 35,349 Value ($000) $103 Avg Close — Range —
Q2 2017
Shares 46,659 Value ($000) $208 Avg Close — Range —
Q1 2017
Shares 67,145 Value ($000) $313 Avg Close — Range —
Q4 2016
Shares 216,238 Value ($000) $1,317 Avg Close — Range —
Q3 2016
Shares 188,211 Value ($000) $1,037 Avg Close — Range —
Q2 2016
Shares 78,475 Value ($000) $298 Avg Close — Range —