SYNERGY PHARMACEUTICALS DEL

CUSIP: 871639308 Class: COM

GREAT WEST LIFE ASSURANCE CO /CAN/'s Holding History (CIK: 0001046192)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018
Shares 22,700 Value ($000) $38 Avg Close — Range —
Q2 2018
Shares 22,700 Value ($000) $39 Avg Close — Range —
Q1 2018
Shares 22,700 Value ($000) $41 Avg Close — Range —
Q4 2017
Shares 22,700 Value ($000) $51 Avg Close — Range —
Q3 2017
Shares 22,700 Value ($000) $59 Avg Close — Range —
Q2 2017
Shares 22,700 Value ($000) $101 Avg Close — Range —
Q1 2017
Shares 22,700 Value ($000) $105 Avg Close — Range —
Q4 2016
Shares 22,700 Value ($000) $139 Avg Close — Range —
Q3 2016
Shares 22,700 Value ($000) $125 Avg Close — Range —
Q2 2016
Shares 22,700 Value ($000) $86 Avg Close — Range —
Q1 2016
Shares 22,700 Value ($000) $62 Avg Close — Range —
Q4 2015
Shares 22,700 Value ($000) $129 Avg Close — Range —
Q3 2015
Shares 22,700 Value ($000) $120 Avg Close — Range —
Q2 2015
Shares 22,700 Value ($000) $188 Avg Close — Range —
Q1 2015
Shares 22,700 Value ($000) $104 Avg Close — Range —
Q4 2014
Shares 22,700 Value ($000) $69 Avg Close — Range —
Q3 2014
Shares 22,700 Value ($000) $63 Avg Close — Range —
Q2 2014
Shares 22,700 Value ($000) $92 Avg Close — Range —