SYNERGY PHARMACEUTICALS DEL

CUSIP: 871639308 Class: COM

Asset Management One Co., Ltd.'s Holding History (CIK: 0001068855)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017
Shares 13,490 Value ($000) $63 Avg Close — Range —
Q4 2016
Shares 13,768 Value ($000) $82 Avg Close — Range —
Q3 2016
Shares 38,878 Value ($000) $208 Avg Close — Range —