SYNERGY PHARMACEUTICALS DEL

CUSIP: 871639308 Class: COM

FIRST TRUST ADVISORS LP's Holding History (CIK: 0001125816)

Note: Option positions (PUT/CALL) are excluded.

Q4 2017
Shares 17,382 Value ($000) $39 Avg Close — Range —
Q3 2017
Shares 13,210 Value ($000) $38 Avg Close — Range —