SYNERGY PHARMACEUTICALS DEL

CUSIP: 871639308 Class: COM

JANUS HENDERSON GROUP PLC's Holding History (CIK: 0001274173)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016
Shares 134,925 Value ($000) $372 Avg Close — Range —
Q4 2015
Shares 134,925 Value ($000) $766 Avg Close — Range —
Q3 2015
Shares 134,925 Value ($000) $714 Avg Close — Range —
Q2 2015
Shares 134,925 Value ($000) $1,118 Avg Close — Range —
Q1 2015
Shares 134,925 Value ($000) $623 Avg Close — Range —
Q4 2014
Shares 134,925 Value ($000) $370 Avg Close — Range —