SYNERGY PHARMACEUTICALS DEL

CUSIP: 871639308 Class: COM

Zurcher Kantonalbank (Zurich Cantonalbank)'s Holding History (CIK: 0001368163)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018
Shares 14,771 Value ($000) $25 Avg Close — Range —
Q2 2018
Shares 14,771 Value ($000) $26 Avg Close — Range —
Q1 2018
Shares 14,771 Value ($000) $27 Avg Close — Range —
Q4 2017
Shares 14,771 Value ($000) $33 Avg Close — Range —
Q3 2017
Shares 3,778 Value ($000) $11 Avg Close — Range —
Q2 2017
Shares 3,778 Value ($000) $17 Avg Close — Range —
Q1 2017
Shares 3,778 Value ($000) $18 Avg Close — Range —
Q4 2016
Shares 3,778 Value ($000) $23 Avg Close — Range —
Q3 2016
Shares 2,825 Value ($000) $16 Avg Close — Range —
Q2 2016
Shares 2,825 Value ($000) $11 Avg Close — Range —
Q1 2016
Shares 2,825 Value ($000) $8 Avg Close — Range —
Q4 2015
Shares 2,825 Value ($000) $16 Avg Close — Range —
Q3 2015
Shares 1,062 Value ($000) $6 Avg Close — Range —