SYNERGY PHARMACEUTICALS DEL

CUSIP: 871639308 Class: COM

CITADEL ADVISORS LLC's Holding History (CIK: 0001423053)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 547,822 Value ($000) $62 Avg Close — Range —
Q3 2018
Shares 37,640 Value ($000) $64 Avg Close — Range —
Q4 2017
Shares 263,448 Value ($000) $587 Avg Close — Range —
Q3 2017
Shares 6,127,332 Value ($000) $17,769 Avg Close — Range —
Q2 2017
Shares 6,003,669 Value ($000) $26,716 Avg Close — Range —
Q1 2017
Shares 5,909,466 Value ($000) $27,538 Avg Close — Range —
Q4 2016
Shares 587,925 Value ($000) $3,580 Avg Close — Range —
Q3 2016
Shares 1,791,095 Value ($000) $9,868 Avg Close — Range —
Q2 2016
Shares 1,692,437 Value ($000) $6,431 Avg Close — Range —
Q1 2016
Shares 553,350 Value ($000) $1,528 Avg Close — Range —
Q4 2015
Shares 2,493,970 Value ($000) $14,141 Avg Close — Range —
Q3 2015
Shares 3,914,655 Value ($000) $20,748 Avg Close — Range —
Q2 2015
Shares 587,247 Value ($000) $4,874 Avg Close — Range —
Q1 2015
Shares 48,573 Value ($000) $224 Avg Close — Range —
Q4 2014
Shares 32,505 Value ($000) $99 Avg Close — Range —
Q3 2014
Shares 19,058 Value ($000) $53 Avg Close — Range —
Q2 2014
Shares 9,388 Value ($000) $38 Avg Close — Range —
Q1 2014
Shares 38,757 Value ($000) $206 Avg Close — Range —