SYNERGY PHARMACEUTICALS DEL

CUSIP: 871639308 Class: COM

Point72 Asset Management, L.P.'s Holding History (CIK: 0001603466)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015
Shares 320,400 Value ($000) $1,817 Avg Close — Range —
Q3 2015
Shares 256,208 Value ($000) $1,358 Avg Close — Range —