SYNTHETIC BIOLOGICS INC

CUSIP: 87164U102 Class: COM

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017
Shares 33,372 Value ($000) $21 Avg Close — Range —
Q4 2016
Shares 173,957 Value ($000) $133 Avg Close — Range —