SYROS PHARMACEUTICALS INC

CUSIP: 87184Q107 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022
Shares 106,700 Value ($000) $127 Avg Close — Range —
Q4 2021
Shares 90,600 Value ($000) $295 Avg Close — Range —
Q3 2021
Shares 172,700 Value ($000) $772 Avg Close — Range —
Q2 2021
Shares 256,100 Value ($000) $1,396 Avg Close — Range —
Q1 2021
Shares 295,800 Value ($000) $2,213 Avg Close — Range —
Q4 2020
Shares 230,800 Value ($000) $2,504 Avg Close — Range —
Q3 2020
Shares 182,100 Value ($000) $1,610 Avg Close — Range —
Q2 2020
Shares 182,300 Value ($000) $1,943 Avg Close — Range —
Q1 2020
Shares 80,400 Value ($000) $477 Avg Close — Range —
Q4 2019
Shares 105,500 Value ($000) $729 Avg Close — Range —
Q2 2019
Shares 38,000 Value ($000) $352 Avg Close — Range —
Q1 2019
Shares 41,000 Value ($000) $375 Avg Close — Range —
Q4 2018
Shares 50,800 Value ($000) $283 Avg Close — Range —
Q3 2018
Shares 55,400 Value ($000) $660 Avg Close — Range —
Q2 2018
Shares 74,000 Value ($000) $756 Avg Close — Range —
Q4 2017
Shares 10,800 Value ($000) $105 Avg Close — Range —