TARGACEPT INC

CUSIP: 87611R306 Class: CMN

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015
Shares 722 Value ($000) $2 Avg Close — Range —
Q1 2015
Shares 722 Value ($000) $2 Avg Close — Range —
Q4 2014
Shares 722 Value ($000) $2 Avg Close — Range —
Q3 2014
Shares 722 Value ($000) $2 Avg Close — Range —
Q2 2014
Shares 722 Value ($000) $3 Avg Close — Range —
Q1 2014
Shares 22,162 Value ($000) $105 Avg Close — Range —
Q4 2013
Shares 23,213 Value ($000) $96 Avg Close — Range —
Q3 2013
Shares 14,628 Value ($000) $78 Avg Close — Range —
Q2 2013
Shares 7,002 Value ($000) $29 Avg Close — Range —