TARGACEPT INC

CUSIP: 87611R306 Class: CMN

Zurcher Kantonalbank (Zurich Cantonalbank)'s Holding History (CIK: 0001368163)

Note: Option positions (PUT/CALL) are excluded.

Q3 2012
Shares 35,000 Value ($000) $171 Avg Close — Range —
Q2 2012
Shares 35,000 Value ($000) $151 Avg Close — Range —
Q1 2012
Shares 35,000 Value ($000) $179 Avg Close — Range —
Q4 2011
Shares 35,000 Value ($000) $195 Avg Close — Range —