TETRAPHASE PHARMACEUTICALS I

CUSIP: 88165N105 Class: COMMON STOCK

FMR LLC's Holding History (CIK: 0000315066)

Note: Option positions (PUT/CALL) are excluded.

Q2 2019
Shares 1,350 Value ($000) $1 Avg Close — Range —
Q1 2019
Shares 845 Value ($000) $1 Avg Close — Range —
Q4 2018
Shares 845 Value ($000) $1 Avg Close — Range —
Q3 2018
Shares 300 Value ($000) $1 Avg Close — Range —
Q4 2017
Shares 989,234 Value ($000) $6,232 Avg Close — Range —
Q3 2017
Shares 1,286,834 Value ($000) $8,802 Avg Close — Range —
Q2 2017
Shares 1,336,034 Value ($000) $9,526 Avg Close — Range —
Q1 2017
Shares 1,377,634 Value ($000) $12,660 Avg Close — Range —
Q4 2016
Shares 1,968,748 Value ($000) $7,934 Avg Close — Range —
Q3 2016
Shares 1,968,906 Value ($000) $7,541 Avg Close — Range —
Q2 2016
Shares 1,968,906 Value ($000) $8,466 Avg Close — Range —
Q1 2016
Shares 1,968,634 Value ($000) $9,115 Avg Close — Range —
Q4 2015
Shares 2,147,834 Value ($000) $21,543 Avg Close — Range —
Q3 2015
Shares 2,148,534 Value ($000) $16,028 Avg Close — Range —
Q2 2015
Shares 3,107,434 Value ($000) $147,417 Avg Close — Range —
Q1 2015
Shares 3,200,234 Value ($000) $117,257 Avg Close — Range —
Q4 2014
Shares 2,974,221 Value ($000) $118,107 Avg Close — Range —
Q3 2014
Shares 2,118,616 Value ($000) $42,267 Avg Close — Range —
Q2 2014
Shares 2,255,945 Value ($000) $23,215 Avg Close — Range —
Q1 2014
Shares 2,141,645 Value ($000) $21,673 Avg Close — Range —
Q4 2013
Shares 2,141,645 Value ($000) $28,955 Avg Close — Range —
Q3 2013
Shares 2,141,645 Value ($000) $24,372 Avg Close — Range —
Q2 2013
Shares 2,141,645 Value ($000) $15,056 Avg Close — Range —