TETRAPHASE PHARMACEUTICALS I

CUSIP: 88165N105 Class: COMMON STOCK

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018
Shares 25,990 Value ($000) $72 Avg Close — Range —
Q2 2018
Shares 34,011 Value ($000) $121 Avg Close — Range —
Q1 2018
Shares 26,601 Value ($000) $82 Avg Close — Range —
Q4 2017
Shares 551,637 Value ($000) $3,475 Avg Close — Range —
Q3 2017
Shares 592,799 Value ($000) $4,055 Avg Close — Range —
Q2 2017
Shares 130,320 Value ($000) $930 Avg Close — Range —
Q1 2017
Shares 126,315 Value ($000) $1,161 Avg Close — Range —
Q4 2016
Shares 164,062 Value ($000) $661 Avg Close — Range —
Q3 2016
Shares 192,543 Value ($000) $737 Avg Close — Range —
Q4 2015
Shares 85,879 Value ($000) $861 Avg Close — Range —
Q3 2015
Shares 36,965 Value ($000) $276 Avg Close — Range —
Q2 2015
Shares 7,765 Value ($000) $368 Avg Close — Range —
Q1 2015
Shares 8,200 Value ($000) $300 Avg Close — Range —
Q2 2013
Shares 18,170 Value ($000) $128 Avg Close — Range —