TETRAPHASE PHARMACEUTICALS I

CUSIP: 88165N105 Class: COMMON STOCK

CANADA PENSION PLAN INVESTMENT BOARD's Holding History (CIK: 0001283718)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 100,000 Value ($000) $134 Avg Close — Range —
Q3 2018
Shares 250,000 Value ($000) $690 Avg Close — Range —
Q2 2018
Shares 50,000 Value ($000) $179 Avg Close — Range —
Q4 2017
Shares 2,554,100 Value ($000) $16,091 Avg Close — Range —
Q3 2017
Shares 2,554,100 Value ($000) $17,470 Avg Close — Range —
Q2 2017
Shares 1,654,100 Value ($000) $11,794 Avg Close — Range —
Q1 2017
Shares 1,654,100 Value ($000) $15,201 Avg Close — Range —
Q4 2016
Shares 1,654,100 Value ($000) $6,666 Avg Close — Range —
Q3 2016
Shares 1,654,100 Value ($000) $6,335 Avg Close — Range —
Q2 2016
Shares 1,976,220 Value ($000) $8,498 Avg Close — Range —
Q1 2016
Shares 1,976,220 Value ($000) $9,150 Avg Close — Range —
Q4 2015
Shares 1,976,220 Value ($000) $19,821 Avg Close — Range —