TETRAPHASE PHARMACEUTICALS I

CUSIP: 88165N105 Class: COMMON STOCK

EVENTIDE ASSET MANAGEMENT, LLC's Holding History (CIK: 0001442891)

Note: Option positions (PUT/CALL) are excluded.

Q4 2017
Shares 463,700 Value ($000) $2,921 Avg Close — Range —
Q3 2017
Shares 463,700 Value ($000) $3,172 Avg Close — Range —
Q2 2017
Shares 600,000 Value ($000) $4,278 Avg Close — Range —
Q1 2017
Shares 600,000 Value ($000) $5,514 Avg Close — Range —
Q4 2016
Shares 600,000 Value ($000) $2,418 Avg Close — Range —
Q3 2016
Shares 600,000 Value ($000) $2,298 Avg Close — Range —
Q2 2016
Shares 600,000 Value ($000) $2,580 Avg Close — Range —
Q4 2015
Shares 139,300 Value ($000) $1,397 Avg Close — Range —
Q3 2015
Shares 174,000 Value ($000) $1,298 Avg Close — Range —
Q2 2015
Shares 290,000 Value ($000) $13,758 Avg Close — Range —
Q1 2015
Shares 290,000 Value ($000) $10,626 Avg Close — Range —
Q4 2014
Shares 290,000 Value ($000) $11,516 Avg Close — Range —
Q3 2014
Shares 300,900 Value ($000) $6,003 Avg Close — Range —
Q2 2014
Shares 300,900 Value ($000) $4,059 Avg Close — Range —
Q1 2014
Shares 300,900 Value ($000) $3,277 Avg Close — Range —
Q4 2013
Shares 96,600 Value ($000) $1,306 Avg Close — Range —