TETRAPHASE PHARMACEUTICALS I

CUSIP: 88165N105 Class: COMMON STOCK

SIMPLEX TRADING, LLC's Holding History (CIK: 0001488542)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 13,429 Value ($000) $15 Avg Close — Range —
Q3 2018
Shares 44,406 Value ($000) $122 Avg Close — Range —
Q1 2018
Shares 30,813 Value ($000) $94 Avg Close — Range —
Q4 2017
Shares 34,596 Value ($000) $217 Avg Close — Range —
Q4 2016
Shares 1,781 Value ($000) $7 Avg Close — Range —
Q2 2016
Shares 2,912 Value ($000) $12 Avg Close — Range —
Q1 2016
Shares 13,570 Value ($000) $62 Avg Close — Range —
Q3 2015
Shares 83,235 Value ($000) $620 Avg Close — Range —
Q2 2015
Shares 8,769 Value ($000) $416 Avg Close — Range —
Q1 2015
Shares 4,532 Value ($000) $166 Avg Close — Range —
Q4 2014
Shares 4,529 Value ($000) $180 Avg Close — Range —