TETRAPHASE PHARMACEUTICALS I

CUSIP: 88165N105 Class: COMMON STOCK

Connor, Clark & Lunn Investment Management Ltd.'s Holding History (CIK: 0001596800)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 11,000 Value ($000) $42 Avg Close — Range —
Q2 2016
Shares 17,500 Value ($000) $75 Avg Close — Range —
Q1 2016
Shares 21,500 Value ($000) $100 Avg Close — Range —