THERAPEUTICSMD INC

CUSIP: 88338N107 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021
Shares 183,651 Value ($000) $65 Avg Close — Range —
Q3 2021
Shares 22,351 Value ($000) $17 Avg Close — Range —
Q1 2021
Shares 491,836 Value ($000) $659 Avg Close — Range —
Q2 2020
Shares 126,224 Value ($000) $158 Avg Close — Range —
Q1 2020
Shares 133,754 Value ($000) $142 Avg Close — Range —
Q4 2019
Shares 1,207,214 Value ($000) $2,921 Avg Close — Range —
Q3 2016
Shares 11,200 Value ($000) $76 Avg Close — Range —