THRESHOLD PHARMACEUTICAL INC

CUSIP: 885807206 Class: CMN

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017
Shares 14,517 Value ($000) $8 Avg Close — Range —
Q1 2016
Shares 54,986 Value ($000) $25 Avg Close — Range —