THRESHOLD PHARMACEUTICAL INC

CUSIP: 885807206 Class: CMN

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q2 2016
Shares 76,100 Value ($000) $48 Avg Close — Range —
Q1 2016
Shares 131,605 Value ($000) $61 Avg Close — Range —
Q4 2015
Shares 200,620 Value ($000) $96 Avg Close — Range —
Q3 2015
Shares 10,700 Value ($000) $44 Avg Close — Range —