TOBIRA THERAPEUTICS INC

CUSIP: 88883P101 Class: COMMON

FMR LLC's Holding History (CIK: 0000315066)

Note: Option positions (PUT/CALL) are excluded.

Q2 2016
Shares 1,294,448 Value ($000) $16,258 Avg Close — Range —
Q1 2016
Shares 1,428,395 Value ($000) $11,684 Avg Close — Range —
Q4 2015
Shares 1,540,248 Value ($000) $15,479 Avg Close — Range —
Q3 2015
Shares 1,279,588 Value ($000) $12,361 Avg Close — Range —