TOKAI PHARMACEUTICALS INC

CUSIP: 88907J107 Class: COM

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017
Shares 169,747 Value ($000) $142 Avg Close — Range —
Q4 2016
Shares 203,934 Value ($000) $199 Avg Close — Range —
Q3 2016
Shares 49,403 Value ($000) $76 Avg Close — Range —
Q4 2015
Shares 18,123 Value ($000) $158 Avg Close — Range —