TREVENA INC

CUSIP: 89532E109 Class: COM

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q2 2018
Shares 950,000 Value ($000) $1,368 Avg Close — Range —
Q1 2018
Shares 950,000 Value ($000) $1,558 Avg Close — Range —
Q4 2017
Shares 950,000 Value ($000) $1,520 Avg Close — Range —
Q3 2017
Shares 950,000 Value ($000) $2,423 Avg Close — Range —
Q2 2017
Shares 950,000 Value ($000) $2,185 Avg Close — Range —
Q1 2017
Shares 857,206 Value ($000) $3,146 Avg Close — Range —
Q4 2016
Shares 450,000 Value ($000) $2,646 Avg Close — Range —
Q3 2016
Shares 450,000 Value ($000) $3,038 Avg Close — Range —
Q2 2016
Shares 450,000 Value ($000) $2,835 Avg Close — Range —
Q1 2016
Shares 450,000 Value ($000) $3,722 Avg Close — Range —
Q4 2015
Shares 450,000 Value ($000) $4,725 Avg Close — Range —
Q3 2015
Shares 450,000 Value ($000) $4,658 Avg Close — Range —