TREVENA INC

CUSIP: 89532E109 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q2 2022
Shares 20,000 Value ($000) $8 Avg Close — Range —
Q1 2022
Shares 222,700 Value ($000) $122 Avg Close — Range —
Q4 2021
Shares 404,698 Value ($000) $236 Avg Close — Range —
Q3 2021
Shares 49,000 Value ($000) $60 Avg Close — Range —
Q1 2021
Shares 814,300 Value ($000) $1,458 Avg Close — Range —
Q4 2020
Shares 57,300 Value ($000) $123 Avg Close — Range —
Q2 2020
Shares 14,700 Value ($000) $22 Avg Close — Range —
Q4 2019
Shares 22,600 Value ($000) $19 Avg Close — Range —
Q3 2019
Shares 19,287 Value ($000) $19 Avg Close — Range —
Q2 2019
Shares 22,900 Value ($000) $24 Avg Close — Range —
Q1 2019
Shares 44,200 Value ($000) $69 Avg Close — Range —
Q4 2018
Shares 62,900 Value ($000) $27 Avg Close — Range —
Q3 2018
Shares 46,500 Value ($000) $99 Avg Close — Range —
Q2 2018
Shares 28,700 Value ($000) $41 Avg Close — Range —
Q4 2015
Shares 15,500 Value ($000) $163 Avg Close — Range —
Q3 2015
Shares 54,700 Value ($000) $566 Avg Close — Range —