TRIUS THERAPEUTICS INC

CUSIP: 89685K100 Class: CMN

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q3 2013
Shares 30,689 Value ($000) $415 Avg Close — Range —
Q2 2013
Shares 31,705 Value ($000) $257 Avg Close — Range —