VERTEX PHARMACEUTICALS INC

CUSIP: 92532f100 Class: COM

FRANKLIN STREET ADVISORS INC /NC's Holding History (CIK: 0001010873)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016
Shares 20,447 Value ($000) $1,625 Avg Close — Range —
Q4 2015
Shares 11,570 Value ($000) $1,456 Avg Close — Range —
Q3 2015
Shares 12,440 Value ($000) $1,296 Avg Close — Range —
Q2 2015
Shares 12,740 Value ($000) $1,574 Avg Close — Range —
Q1 2015
Shares 14,660 Value ($000) $1,729 Avg Close — Range —
Q4 2014
Shares 23,305 Value ($000) $2,769 Avg Close — Range —
Q3 2014
Shares 22,835 Value ($000) $2,565 Avg Close — Range —
Q2 2014
Shares 22,835 Value ($000) $2,162 Avg Close — Range —
Q1 2014
Shares 35,835 Value ($000) $2,534 Avg Close — Range —
Q4 2013
Shares 35,835 Value ($000) $2,663 Avg Close — Range —